What does NAD do?
NAD is a molecule every cell uses to shuttle energy and run repair enzymes — and its levels decline with age, which is why it anchors so much longevity research.
This topic collects our articles on NAD injections and the science around them: what NAD actually does, what supplementation research shows, side effects, and how injectable NAD compares with oral precursors like NMN and NR. Injectable NAD through Promise is prescription-only after a provider review. Oral precursors and injections are not interchangeable, and the articles below explain the difference.
5 articles on this topic
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How Long Do Peptides Take to Work?
Peptide timelines range from hours on a lab test to months on a scale. The useful answer depends on the molecule, the outcome being measured and the quality of the evidence behind it.
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NAD Injection Dosage: What Human Studies Used
There is no validated subcutaneous or intramuscular NAD+ schedule. The best-known IV pharmacokinetic study used 750 mg over six hours, so a prescriber must set route, concentration, amount and frequency together.
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Is NAD a Peptide? What NAD+ Actually Is
NAD+ is a dinucleotide coenzyme, not a peptide. Its chemistry, cellular jobs, and evidence are different from the peptide therapies it often appears beside.
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NAD Injection Side Effects: What Is Reported
Published intravenous data describe transient infusion-associated symptoms in one small retrospective series and no reported adverse events in an earlier slow-infusion pilot; because the studies differed in design and did not randomize infusion rate, they do not establish speed as the cause.
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A Patient's Guide to NAD+ Injections
NAD+ is a coenzyme found in every living cell, yet most human trial data comes from oral precursors like NR and NMN — including a 2025 meta-analysis in adults with mean ages of 61 to 83 that found no significant muscle benefit.