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Feeling Cold on Tirzepatide: An Autumn Guide
Feeling chilly can accompany weight loss, but persistent coldness deserves a closer look. Here's what the labels say and what cold weather means for storage.
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Ozempic Face: What Facial Changes Really Mean
Ozempic face means a face looking less full after weight loss. Small studies document changes, but they cannot settle whether the drug has a direct effect.
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STRIDE Trial Semaglutide: Walking Results
Semaglutide was associated with better treadmill walking in people with leg artery disease and type 2 diabetes. Here are the numbers, side effects and limits of STRIDE.
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Egrifta Prescribing Information, Explained
Egrifta WR’s label covers one HIV-related use, a daily dose, four contraindications, monitoring, side effects, and product-specific storage. WR and SV directions cannot be swapped.
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IGF-1 Levels by Age: Reading Your Lab Result
IGF-1 levels by age usually decline after early adulthood. Your lab's range puts the number in context; trial increases aren't treatment targets.
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10 Questions to Ask Before BPC-157
Ten questions explain what a BPC-157 visit needs to cover, from medical history and evidence limits to sport testing and follow-up.
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Sermorelin Myths: 10 Claims Checked
Sermorelin can stimulate growth-hormone release. Ten familiar claims about aging, muscle, sleep and safety go further than the human studies support.
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STEP 5 Trial Results: Semaglutide at Two Years
In STEP 5, average weight loss was 15.2% with semaglutide versus 2.6% with placebo at two years. The plateau, side effects and two calculations explain what held up.
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Who Discovered Ghrelin? Kojima and Kangawa
Masayasu Kojima, Kenji Kangawa and colleagues identified ghrelin in 1999. Earlier peptide and receptor discoveries set up the finding; appetite studies followed.
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Who Discovered Semax? Its Russian Origins
Igor Ashmarin, Nikolai Myasoedov and a Moscow team developed Semax. Its history runs from modified hormone fragments to Russian registration and U.S. review.
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Semaglutide and Gout: It Isn't a Gout Treatment
Semaglutide may lower uric acid, but fewer gout attacks remain unproven. New findings make a gout history and a flare plan part of the prescribing conversation.
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Semaglutide Knee Osteoarthritis: What STEP 9 Found
In STEP 9, adults with obesity had greater average knee-pain and weight reductions with semaglutide. The trial did not establish cartilage repair.
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Tesamorelin Fatty Liver Trial: What It Found
A 12-month trial found less liver fat and less worsening of scarring with tesamorelin. Its 61 participants had HIV, a virus that weakens the immune system, which limits what the findings mean for everyone else.
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What Is Food Noise? Meaning and GLP-1 Evidence
Food noise means intrusive food thoughts that are hard to set aside. GLP-1 studies offer evidence about cravings and eating control, while the term itself is still being defined.
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Zenagamtide: Amycretin’s New Name, Still in Trials
Zenagamtide is amycretin’s new name: an experimental drug being tested as a weekly shot and a daily pill. Here’s what the trials actually found.
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Epitalon Telomeres: What the Studies Actually Show
The claim comes from cells studied outside the body. Those findings haven't established a longer or healthier life for people taking epitalon.
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Who Discovered NAD? The History Behind NAD+
Harden and Young found NAD's activity in yeast experiments, with a detailed paper in 1906. The vitamin, Nobel and longevity chapters came later.
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TB-500 Myths: Ten Claims Checked Against Studies
TB-500's benefits in humans have not been established. Ten common claims get graded against the actual molecule, study and outcome behind them.
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Tirzepatide and Thyroid: Levothyroxine Checks
An underactive thyroid doesn't automatically rule out tirzepatide. Weight loss and changes in tablet absorption can make a thyroid-dose review worthwhile.
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OASIS 4 Trial Results: 13.6% Weight Loss Explained
The daily 25 mg tablet averaged 13.6% weight loss versus 2.2% with placebo at 64 weeks. The 16.6% headline assumes continued treatment.
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