Calming & Stress Relief · Rx only

DSIP, prescribed — not just shipped.

Skip the gray-market guesswork. A licensed clinician reviews your health history, a licensed U.S. pharmacy compounds your prescription, and a care team stays with you after it ships.

$243 / mo$270 as a single month · $648 for a 3-month supply

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A licensed clinician reviews every request. If DSIP fits your health history, they write your prescription and your pharmacy takes it from there.

Licensed U.S. providers Licensed U.S. pharmacy All 50 states + D.C.

Requires an online medical evaluation. Prescribed only when a licensed provider determines it's appropriate.

A licensed clinician in a consultation room
DSIP vial and spec card
DSIP · Rx only
1

Share your health history

DSIP has its own online clinical questionnaire — your history, medications, and goals.

2

Your answers get a careful review

A clinician reads your history and takes the time to get it right before anything is prescribed.

3

Your pharmacy ships

Compounded for your prescription and shipped cold-chain, with care-team check-ins after.

The safe way to take DSIP seriously

DSIP is easy to find online and hard to trust there. Promise works the way medicine is supposed to work — a clinician decides, a licensed pharmacy fills, and someone stays accountable to you.

A real prescription

Prescribed for you specifically, after a real look at your health history — never pulled off a shelf.

A real pharmacy

Your prescription is compounded for you by a licensed U.S. pharmacy — not a mystery vial from an unregulated website.

Real oversight

Temperature-safe shipping, follow-up check-ins, and a care team that answers — before and after your medication arrives.

Product details
Form
Injectable vial (subcutaneous), 1 mg per mL
Supply
28-day supply
Pharmacy
Compounded by a licensed U.S. pharmacy
Availability
Ships to all 50 states + D.C.; not all treatments are available in every state

A nine-amino-acid neuropeptide

DSIP was isolated in 1977 from the cerebral venous blood of sleeping rabbits. Research interest since has centered on slow-wave sleep architecture and the stress axis.

The name is historical

It was named for the experiment that found it, not for a demonstrated effect. Human evidence is limited and inconsistent, and we say so rather than lean on the label.

Prescribed, never simply supplied

A licensed provider reviews your history and decides whether DSIP fits it.

In brief.

DSIP has the most misleading name in this catalog, and it is worth saying so before anything else. Delta Sleep-Inducing Peptide was named in 1977 for the conditions under which it was discovered, not for an effect established in people. The human evidence that it induces sleep is limited and inconsistent, and we are not going to pretend otherwise.

What remains is a genuinely interesting research subject: a nine-amino-acid peptide studied in relation to slow-wave sleep architecture, the stress axis, and hormone regulation. It is prescribed only when a licensed provider reviews your health history and determines it is appropriate for you.

Where the name came from

Swiss researchers isolated the peptide from the cerebral venous blood of rabbits during electrically induced sleep and named it for the experiment. That is the entire origin of the word inducing in its name — a description of the conditions in the room, carried forward for nearly fifty years as though it were a finding.

The label stuck, and it has been doing promotional work ever since that the data never authorized. Anyone who reads the name as a claim is reading a 1977 lab note, not a clinical result. Naming a molecule after what you hope it does is a very old habit in pharmacology, and DSIP is one of the cleaner examples of the trouble it causes.

What the research actually examines

The published work looks at a few distinct questions. One line concerns sleep architecture — whether administration changes the proportion of slow-wave, delta-frequency sleep on EEG. Another concerns the hypothalamic-pituitary-adrenal axis, where DSIP has been studied in relation to ACTH and cortisol signaling and the broader stress response. Older literature also examined it in pain and withdrawal contexts.

Most of that work is preclinical. The human studies are small, several are decades old, and they do not agree with each other; some found no measurable change in the endpoints they tracked. There is no modern trial program that settles the question either way.

That is an unsatisfying answer, and it is the accurate one. A compound can be worth studying and still be unproven, and describing it honestly is the only version of this page worth publishing.

What we are not claiming

DSIP is not a treatment for insomnia, sleep apnea, or any diagnosed sleep disorder, and it is not a substitute for having one evaluated. If you are not sleeping, that is a symptom with causes worth finding — breathing, thyroid, mood, alcohol, medication timing, shift work — and nearly all of them have better-supported answers than a peptide does.

This matters for how a visit goes. A provider who reads your intake and sees an untreated sleep problem is likely to point you toward evaluating it rather than write a prescription, and that is the system working, not failing.

How DSIP is prescribed

Everything starts with an intake questionnaire built for this compound: your health history, current medications, sleep and stress history, and what you are actually trying to address. A licensed provider reads it and decides.

If DSIP is a reasonable fit for your history, they write the prescription and set the protocol. Not everyone qualifies, and given how thin the evidence here is, the clinician gate carries more weight in this category than in most.

What treatment looks like

If you are prescribed, your medication is compounded and dispensed by a licensed U.S. pharmacy, and shipped in discreet, temperature-safe packaging. Dosing and timing come from your provider's protocol rather than from a schedule found online.

From there it is follow-up. Your care team checks in, and anything that needs to change, changes with a clinician involved. DSIP sits in our calming and stress relief category, alongside the fundamentals it cannot replace — a consistent schedule, a dark room, less alcohol, a real look at what is keeping you up. The promise you made to yourself is better served by that honesty than by a compound that oversells itself in its own name.

Common questions

What is DSIP?

DSIP is a nonapeptide — a chain of nine amino acids — first isolated in 1977 from the cerebral venous blood of rabbits during electrically induced sleep. Research interest since has centered on slow-wave sleep architecture, on the hypothalamic-pituitary-adrenal axis and stress-hormone signaling, and on related neuroendocrine questions. It is one of the older neuropeptides in circulation and one of the least settled.

Does DSIP induce sleep?

We do not claim that, and the evidence does not let us. The name comes from the 1977 experiment that isolated the peptide, not from a demonstrated effect in people. Human studies have been few, small, and inconsistent, with several finding no measurable change in the sleep measures they tracked. The honest description is a peptide studied in relation to sleep architecture and the stress axis, with a name that has been doing promotional work the data never authorized.

Can I use DSIP for insomnia?

DSIP is not a treatment for insomnia, sleep apnea, or any diagnosed sleep disorder, and it should not stand in for having one evaluated. Persistent sleeplessness has causes worth finding — breathing, thyroid, mood, medications, alcohol, timing — and most of them have better-supported answers than a peptide.

Is DSIP FDA-approved?

No. DSIP is not FDA-approved. It is a compounded medication, and compounded medications are not reviewed by the FDA for safety, effectiveness, or quality. It is prepared by a licensed U.S. compounding pharmacy against a prescription written for you specifically, after a licensed provider has reviewed your health history.

Do I need a prescription, and how does the visit work?

Yes. You complete the intake questionnaire built for DSIP, which is its own clinical form covering your health history, medications, sleep and stress history, and what you are trying to address. A licensed provider reviews your answers and prescribes only when DSIP is appropriate for you. If you are prescribed, a licensed U.S. pharmacy compounds and dispenses your medication and ships it in temperature-safe packaging, with follow-up check-ins from your care team.

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