A compounded medication is prepared by a licensed pharmacy for an individual prescription rather than manufactured in a factory. It's how providers prescribe compounded peptides and other molecules that have no commercial version and adjust formulations to a patient — and it comes with its own rules: compounded medications are not FDA-approved, and quality depends on the pharmacy's standards.

These articles explain how compounding works, how it's regulated, and what that means for the treatments you're prescribed.

226 articles on this topic

  1. A woman sits on a stool beside a kitchen window with a wooden bowl

    Compounded Semaglutide Adverse Events: FDA Update

    FDA now lists 990 adverse-event reports associated with compounded semaglutide and more than 730 with compounded tirzepatide. The counts matter, but they are reports rather than proof of cause or a rate of harm.

    September 22, 2026 · Nadia Okonjo, Health Writer

  2. A man sits on a stool in a greenhouse holding gardening gloves

    FLOW Trial Semaglutide Results: What 24% Means

    FLOW followed 3,533 adults with type 2 diabetes and chronic kidney disease. The headline was a 24% lower risk for a bundle of serious kidney and cardiovascular outcomes, not a promise that kidney disease would disappear.

    September 22, 2026 · Elena Marsh, Health Writer

  3. A woman stands beside a bicycle in a quiet lane with a glass of water

    Semaglutide Myths: 10 Claims Checked

    Ten common semaglutide claims, checked against clinical trials, current prescribing information, and FDA findings.

    September 22, 2026 · Elena Marsh, Health Writer

  4. An empty window seat with a ball of yarn

    Tesamorelin Clinical Trials: What the Studies Show

    The large trials found less visceral abdominal fat in adults with HIV-associated lipodystrophy. They did not test general weight loss, anti-aging, or the compounded formulations sold today.

    September 22, 2026 · Priya Raman, Health Writer

  5. A woman sits on the bottom step of a staircase holding an apple

    Tirzepatide Injection Site Reaction: What to Know

    A small red, itchy, sore patch or raised spot can be a tirzepatide injection site reaction. The Zepbound label reports these reactions in 6% to 8% of treated adults, but a spreading or whole-body reaction is a different concern.

    September 22, 2026 · Julian Reyes, Health Writer

  6. Two friends sit together on a sofa in a quiet living room

    20 Percent Weight Loss: What the Numbers Show

    Twenty percent weight loss is 40 pounds from a 200-pound starting weight. In two large trials, that headline also came with changes in waist size, blood pressure and lab results—but it was an average, not a promise.

    September 22, 2026 · Priya Raman, Health Writer

  7. A man sits on a bench between sets in a quiet gym with a folded towel

    Who Discovered GHRH? The Two 1982 Teams

    Two independent teams identified GHRH in 1982, using an unexpected clue from pancreatic tumors. Their papers opened the path to sermorelin, tesamorelin and CJC-1295.

    September 22, 2026 · Julian Reyes, Health Writer

  8. A driftwood log above a quiet beach

    Generic Tirzepatide: Under Review, Not Approved

    FDA has accepted applications for proposed generic tirzepatide autoinjectors, but none can be sold in the United States yet. Review, approval and launch are three different milestones.

    September 22, 2026 · Julian Reyes, Health Writer

  9. A man sits on a ladder in an orchard beside a basket of apples

    KPV FDA Review: What the July Vote Really Changed

    KPV has never been approved as a U.S. drug. A July 2026 advisory vote favored possible 503A listing, but it did not change the list or approve a product.

    September 22, 2026 · Nadia Okonjo, Health Writer

  10. One plain ceramic mug on bare wood, a close view

    MOTS-c Exercise Claims: What the Studies Show

    MOTS-c is called an exercise mimetic because exercise raises it in people and administered MOTS-c changed running performance in mice. No published human trial shows that taking it improves a workout.

    September 21, 2026 · Priya Raman, Health Writer

  11. A woman sits on a park bench under trees holding a tennis ball

    Who Discovered TB-500? The Full Story

    The short answer starts with Teresa Low, Shu-Kuang Hu, and Allan Goldstein, who sequenced thymosin beta-4 in 1981. The seven-amino-acid fragment now called TB-500 came later, and the record does not name one inventor.

    September 21, 2026 · Nadia Okonjo, Health Writer

  12. A woman sits on a blanket in a meadow beside a basket of apples

    BPC-157 News Update: September 2026

    A July FDA advisory vote moved the conversation forward, but it did not change the law or establish that BPC-157 works in people. A new rat study adds evidence, with the same important limit: it was not a human trial.

    September 21, 2026 · Elena Marsh, Health Writer

  13. Two friends sit together on a bench in a bright entryway

    Hims Peptides: What Hims & Hers Plans to Sell

    Hims & Hers says a peptide and wellness category is coming, but the rollout is phased. Some offerings are planned for 2026, while BPC-157 depends on unfinished FDA rulemaking.

    September 21, 2026 · Priya Raman, Health Writer

  14. A woman sits on a sofa in a quiet living room holding a pear

    What Is an IND? A Plain-English FDA Guide

    An IND is the filing that lets a sponsor begin testing an investigational drug in people. It opens a research path, not a sales or prescription path.

    September 21, 2026 · Elena Marsh, Health Writer

  15. A man sits on a stool beside a kitchen window peeling an orange

    5 Percent Weight Loss Benefits: Study Numbers

    Five percent can be a meaningful first milestone. Here's what studies measured in blood sugar, blood pressure, and sleep, and where the numbers stop being a useful prediction.

    September 20, 2026 · Julian Reyes, Health Writer

  16. A woman sits at a plain kitchen table with a wooden bowl

    BPC-157 and Alcohol: Can You Drink Safely?

    No published human study has tested the combination. The alcohol claims come from experiments in mice and rats, which cannot establish a safe drinking amount or a hangover remedy.

    September 20, 2026 · Priya Raman, Health Writer

  17. A man sits on a blanket in a meadow holding a pear

    SELECT Trial Semaglutide Results: What 20% Means

    SELECT recorded fewer major heart and blood-vessel events with branded semaglutide. Here is what the 20% headline means, who was studied, and where the evidence stops.

    September 20, 2026 · Julian Reyes, Health Writer

  18. A man sits at the end of a lakeside dock with a folded scarf

    Who Discovered Kisspeptin? The People Behind It

    Danny Welch's cancer research started the story in 1996. Other teams found the peptide, connected it to puberty, and brought it into human studies.

    September 20, 2026 · Nadia Okonjo, Health Writer

  19. A folded cream towel on warm stone, a close view

    FDA Category 2 Bulk Drug Substances: What It Means

    Category 2 means FDA has identified significant safety concerns about a nominated compounding ingredient. Here is what the category tells a patient, and why leaving it does not mean approval.

    September 20, 2026 · Elena Marsh, Health Writer

  20. A woman sits on a bench beside an allotment shed holding gardening gloves

    Gray Market Peptides: What Johns Hopkins Found

    Johns Hopkins says the market for unverified peptide vials is growing much faster than the human evidence. The useful question is what a prescription and a pharmacy change.

    September 20, 2026 · Nadia Okonjo, Health Writer

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