With peptides and GLP-1 medications, dose is most of the story: how much, how often, how to step up without inviting side effects, and how to reconstitute a vial correctly. These articles collect what we've written on peptide dosing — titration schedules, injection frequency, microdosing debates, and technique.

One thing you won't find is a personal protocol: that's your prescriber's job. Every Promise treatment comes with provider oversight, and dosing decisions belong in that conversation. Where a compound has its own dosing article, you'll find the specifics there.

62 articles on this topic

  1. An empty armchair beside a window

    Zepbound Prescribing Information, Explained

    The current label is revised August 2026. It covers two uses, a weekly dose ladder, two absolute contraindications, the boxed thyroid warning, common stomach side effects, pregnancy, and four delivery formats.

    September 18, 2026 · Elena Marsh, Health Writer

  2. A woman sits on a sofa in a quiet living room peeling an orange

    Kisspeptin Dose: What Human Studies Actually Used

    There is no standard kisspeptin dose to copy from a study. Human trials used different peptide forms, routes, and schedules, so a prescription has to be set for the person and the clinical goal.

    September 17, 2026 · Nadia Okonjo, Health Writer

  3. A boulder beside a quiet trail

    Where to Inject CJC-1295 Ipamorelin: Site Guide

    CJC-1295/ipamorelin is generally given into fatty tissue just under the skin. Common areas include the abdomen, thigh, back of the upper arm, and upper buttock, but the pharmacy label sets the sites for the exact prescription.

    September 17, 2026 · Priya Raman, Health Writer

  4. A woman sits on the bottom step of a staircase with a ball of yarn

    PT-141 Half-Life Is About 2.7 Hours

    The number is short, but it is not a stopwatch for how long someone feels an effect. Here is what the label's timing, clearance range, and safety limits actually mean.

    September 16, 2026 · Julian Reyes, Health Writer

  5. A man sits on a stool beside a kitchen window with a wooden bowl

    TB-500 10 mg: What the Vial Size Really Means

    A 10 mg mark states the total peptide mass the vial is meant to contain. It is not a per-injection dose, a concentration, or proof that an unverified vial contains what its label claims.

    September 16, 2026 · Elena Marsh, Health Writer

  6. A man sits on a driftwood log above a quiet beach with a folded scarf

    PT-141 10mg Vial: What That Number Means

    Ten milligrams describes what is in the whole vial. It does not tell you what to draw up, how many uses you have, or how a nasal product compares; those answers come from the prescription and pharmacy label.

    September 15, 2026 · Julian Reyes, Health Writer

  7. A man sits on a small balcony beside a watering can

    Sermorelin Half-Life: About 11 to 12 Minutes

    Sermorelin leaves the bloodstream in minutes, but the growth-hormone pulse it starts can last for hours. Those are two different clocks, and neither is a personal dosing or drug-testing deadline.

    September 15, 2026 · Priya Raman, Health Writer

  8. A woman sits on the front steps of a house beside a basket of apples

    Where to Inject MOTS-c: What the Evidence Says

    The available human trial records point to a subcutaneous shot into the fatty layer beneath the skin. The pharmacy label and prescriber—not an online injection map—set the site for a specific MOTS-c preparation.

    September 15, 2026 · Elena Marsh, Health Writer

  9. A woman sits in an armchair by a bright windowsill holding a plain ceramic mug

    SS-31 Protocol: What the Trials Actually Used

    There is no single SS-31 cycle supported by human research. The useful evidence is narrower: a labeled plan for one rare disease and several trial schedules that cannot be copied into personal dosing advice.

    September 14, 2026 · Priya Raman, Health Writer

  10. A woman seated calmly in a simple bedroom before bedtime

    When to Take Sermorelin: Why Bedtime Is Common

    Bedtime is the usual convention because the body's largest growth-hormone pulse often follows deep sleep. It is a rhythm to work with, not proof that one clock time fits everyone.

    September 14, 2026 · Nadia Okonjo, Health Writer

  11. A man in a cream jumper sits by a window with a mug in soft morning light

    Tesamorelin 10 mg: What the Vial Number Means

    A tesamorelin 10 mg label describes the total peptide in the vial, not the amount in one injection. The prescribed amount, liquid volume, and days of supply come from the pharmacy label and provider's plan.

    September 13, 2026 · Julian Reyes, Health Writer

  12. A woman in a sage knit top and navy trousers sits with a mug beside a bedroom window

    Selank Dosage: What Human Studies Actually Used

    Russian human studies most clearly report 2.7 mg per day intranasally for 14 days, but that fixed study protocol is not a personal dosing guide and does not convert to an injectable Semax/Selank blend.

    September 12, 2026 · Julian Reyes, Health Writer

  13. A woman in a sage top sits on an entryway bench and laces a shoe beneath a window

    When to Take MOTS-c: What Human Research Says

    No human trial has shown that morning, night, or a workout window is best. The exercise link is real but easy to overread: researchers measured the MOTS-c people made themselves, not the effect of a timed dose.

    September 12, 2026 · Elena Marsh, Health Writer

  14. A woman sits on the edge of a low bed in a bare, sunlit bedroom, hands resting in her lap

    How to Use PT-141: It's As-Needed, Not Daily

    PT-141 is taken before anticipated activity rather than on a daily schedule. Here is what the approved label sets out, what a compounded vial changes, and what the prescriber decides.

    September 11, 2026 · Nadia Okonjo, Health Writer

  15. A woman in a rust-colored jacket and full-length dark trousers walks toward the camera along a wooded path

    MOTS-c Cycle: Nobody Has Established One

    The word “cycle” came from bodybuilding, not from any MOTS-c research. Every study that has actually given the peptide — the mouse work, and the one human trial now running — dosed it straight through, with no weeks off.

    September 11, 2026 · Priya Raman, Health Writer

  16. A middle-aged man sits with a mug in an armchair by a sunlit morning window

    Sermorelin for Muscle Growth: Evidence Is Limited

    Sermorelin can raise growth-hormone pulses, but that does not automatically build muscle. The human studies are small, and they have not shown a reliable strength benefit.

    September 11, 2026 · Julian Reyes, Health Writer

  17. A woman seated at a bright kitchen counter peeling an orange

    Tirzepatide 3 Month Supply: What You Get

    Three months usually means a series of monthly dose packages, not one vial kept open for 90 days. The prescription, storage dates, and billing period each answer a different part of the question.

    September 11, 2026 · Elena Marsh, Health Writer

  18. A man in a navy shirt and stone trousers rests on a linen sofa holding a plain mug

    BPC-157 Dosage by Body Weight: No Human Formula

    There is no validated weight-based BPC-157 dose for people. The micrograms-per-kilogram numbers online were lifted from rat experiments, not human dose-finding trials.

    September 10, 2026 · Priya Raman, Health Writer

  19. A man sits on a wooden bench beneath a window, lacing a shoe, facing the camera

    Tesamorelin Cycle: Why Doctors Talk About Duration

    There is no on-and-off tesamorelin cycle in the research. The trials ran it daily for 26 weeks and then 52 — and when people stopped, the visceral fat came back.

    September 10, 2026 · Elena Marsh, Health Writer

  20. A man sits in a linen armchair beside a sunlit window, a plain mug held in both hands.

    Kisspeptin and Testosterone: Pattern Beats Amount

    A study published on August 3, 2026 gave 15 healthy men kisspeptin-10 three different ways. Five days of it around the clock and the pituitary stopped answering; eight hours on and sixteen off, and it kept answering for twelve days.

    September 9, 2026 · Nadia Okonjo, Health Writer

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