GLP-1 is a hormone your gut releases after you eat — it tells your brain you're full and helps your body manage blood sugar. GLP-1 medications (semaglutide, tirzepatide, and newer molecules) copy that signal, which is why they're so widely studied for weight management and metabolic health.

The articles below explain how these medications work, what the research actually shows, and what side effects and dosing schedules look like in practice. Promise offers compounded GLP-1 medications by prescription only: a licensed provider reviews every request, and not everyone qualifies.

136 articles on this topic

  1. A woman sits at a kitchen table facing the camera, holding a plain white mug in both hands.

    Mounjaro vs Zepbound: Same Drug, Two Labels

    Both pens hold tirzepatide and run the same dose ladder. What differs is the use printed on the carton — and that is what your insurer reads.

    September 9, 2026 · Priya Raman, Health Writer

  2. A parent peels an orange at a bright kitchen counter

    Semaglutide for Children: What STEP Young Means

    Semaglutide for children ages 6 to 11 has encouraging new trial results, but the news has not changed who can receive Wegovy under its current label. The evidence is promising, early, and best read with a pediatrician.

    September 9, 2026 · Julian Reyes, Health Writer

  3. A woman sits beside a raised garden bed holding a small pot of seedlings

    What Is Semaglutide Used For? A Plain Guide

    Semaglutide has different jobs depending on the brand: blood sugar control, heart or kidney risk reduction, long-term weight management, or certain liver disease. Here is the plain list before a first visit.

    September 9, 2026 · Julian Reyes, Health Writer

  4. A woman in a blue long-sleeve shirt sits on a bench beneath a window, holding a plain ceramic mug in both hands

    Best Tirzepatide Compounding Pharmacy Checklist

    The best choice is a pharmacy you can verify: licensed, tied to a real prescription, clear about sterile preparation, and accountable for the vial after it leaves the building.

    September 8, 2026 · Priya Raman, Health Writer

  5. A woman in a blue knit top peels an orange at a bright kitchen counter

    Tirzepatide Pills Don't Exist. Here's What Does

    There is no oral tirzepatide, either as a brand product or a validated compounded pill. Real GLP-1 tablets contain semaglutide or orforglipron, which are different medicines.

    September 8, 2026 · Nadia Okonjo, Health Writer

  6. A woman sits on the wooden edge of a raised garden bed, a small pot of seedlings held in her lap.

    Zepbound vs Wegovy: Two Drugs, Not Two Brands

    They get compared like two versions of one medicine. They are not — different molecules, different makers, and different lists of what each one is cleared to treat.

    September 8, 2026 · Elena Marsh, Health Writer

  7. Two friends discuss a health decision over coffee in quiet armchairs

    No Shortcut: The Peptide FDA Approval Process

    Mimrylo’s August 2026 approval is a useful look at the whole path: permission to begin human studies, three trial phases, a full application, manufacturing review, and a label limited to one use.

    September 8, 2026 · Elena Marsh, Health Writer

  8. Two friends in armchairs talk over plain mugs in a quiet living room

    Retatrutide Lawsuit: It Is Still Investigational

    Lilly sued six sellers in August, but the practical answer predates the cases: retatrutide remains investigational and no pharmacy can lawfully compound it for patients.

    September 8, 2026 · Julian Reyes, Health Writer

  9. A middle-aged woman sits in an armchair by a sunlit morning window holding a plain mug

    Semaglutide and Heart Health: What Studies Show

    Semaglutide has been linked to fewer major cardiovascular events in a specific high-risk group, and to better symptoms in one type of heart failure. The numbers are meaningful, but they do not apply to every heart or every formulation.

    September 7, 2026 · Nadia Okonjo, Health Writer

  10. A woman sits in a linen armchair beside a bright window, facing the camera, holding a plain ceramic mug in both hands

    Semaglutide and Vision: What's Real, What's Rare

    Most people never have an eye problem because of semaglutide. Two things do come up, though, and they get mixed together constantly — so here is what each one actually is.

    September 7, 2026 · Elena Marsh, Health Writer

  11. A man in a pale blue shirt walks toward the camera on a quiet desert trail

    Semaglutide for Heart Failure Now Has ESC Support

    Europe's 2026 heart-failure guideline now says semaglutide or tirzepatide should be considered for symptomatic patients with obesity and an ejection fraction of at least 45%. The recommendation is about symptoms, walking capacity, and quality of life—not proof that semaglutide prevents death.

    September 7, 2026 · Julian Reyes, Health Writer

  12. A woman in a grey wool cardigan and full-length navy trousers sits in a linen armchair beside a bright window, a plain mug held in both hands

    Tirzepatide Diabetic Retinopathy: Who It's For

    The tirzepatide diabetic retinopathy warning landed on both U.S. labels in August 2026. It asks for eye monitoring in people who already have the condition — not a finding that the medicine harms eyes.

    September 7, 2026 · Priya Raman, Health Writer

  13. A man in a navy long-sleeve jacket and full-length grey trousers walks along a wide gravel path toward the camera, low hills behind him

    Tirzepatide Heart Benefits: Who the Label Covers

    In August 2026 the brand-name version of tirzepatide gained a new use on its label: lowering the risk of heart attack, stroke and cardiac death in adults with type 2 diabetes. Here is what that covers, and what it doesn't.

    September 7, 2026 · Nadia Okonjo, Health Writer

  14. A man in a navy crew-neck jumper and full-length grey trousers sits at a kitchen table peeling an orange

    Tirzepatide vs Ozempic: What You're Comparing

    Ozempic is a brand of semaglutide, approved for type 2 diabetes. Tirzepatide is a different molecule with its own brands — so the comparison most people want is between two drugs, not a drug and a label.

    September 7, 2026 · Julian Reyes, Health Writer

  15. A woman in a blue knit top sits by a bright windowsill holding a plain ceramic mug

    Compounded Tirzepatide Court Ruling Upholds FDA

    The Fifth Circuit left FDA's tirzepatide shortage decision in place. That closes the broad shortage-era compounding route, but it does not erase the narrower rules for an identified patient.

    September 7, 2026 · Priya Raman, Health Writer

  16. A man in a blue shirt arranges oranges in a bright matte-white kitchen

    GLP-1 Patches: Do They Work?

    GLP-1 patches sold online are usually supplement stickers, not semaglutide or tirzepatide. Ordinary patches cannot move these large peptide drugs across intact skin in a predictable dose.

    September 6, 2026 · Julian Reyes, Health Writer

  17. A woman sits at the edge of a raised garden bed holding a small pot of seedlings

    Semaglutide and Aging: The New Study Is in Mice

    A new Nature study found longer life and better physical function in old female mice given semaglutide. It did not test people, so it cannot tell us that semaglutide slows human aging or adds years to human life.

    September 6, 2026 · Elena Marsh, Health Writer

  18. A woman in a sage knit top rests in an armchair with a mug by a window

    Semaglutide L-Carnitine: What the Additive Means

    Some compounders add L-carnitine for its role in fat metabolism. The rationale is real biology, but no human trial shows that mixing it with semaglutide improves weight-loss outcomes.

    September 6, 2026 · Elena Marsh, Health Writer

  19. Two friends sit in armchairs by a window and talk over plain ceramic mugs

    FDA Peptide Warning Letters: What They Mean

    FDA’s five August 24 letters targeted the way online sellers presented injectable peptides for people—not peptide molecules as a class. Here’s what changed, what didn’t, and how a prescription route differs.

    September 6, 2026 · Julian Reyes, Health Writer

  20. A man sits with a mug in an armchair beside a sunlit window in the morning

    Is Semaglutide a GLP-1? What the Class Means

    Yes. Semaglutide is a GLP-1 receptor agonist and an engineered peptide. Those labels describe two different things: the receptor it activates and the structure of the medication.

    September 5, 2026 · Julian Reyes, Health Writer

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