Topic

GLP-1 medications

GLP-1 is a hormone your gut releases after you eat — it tells your brain you're full and helps your body manage blood sugar. GLP-1 medications (semaglutide, tirzepatide, and newer molecules) copy that signal, which is why they're so widely studied for weight management and metabolic health.

The articles below explain how these medications work, what the research actually shows, and what side effects and dosing schedules look like in practice. Promise offers compounded GLP-1 medications by prescription only: a licensed provider reviews every request, and not everyone qualifies.

88 articles on this topic

  1. A middle-aged woman sits in an armchair by a sunlit morning window holding a plain mug

    Semaglutide and Heart Health: What Studies Show

    Semaglutide has been linked to fewer major cardiovascular events in a specific high-risk group, and to better symptoms in one type of heart failure. The numbers are meaningful, but they do not apply to every heart or every formulation.

    September 7, 2026 · Nadia Okonjo, Health Writer
  2. A woman sits in a linen armchair beside a bright window, facing the camera, holding a plain ceramic mug in both hands

    Semaglutide and Vision: What's Real, What's Rare

    Most people never have an eye problem because of semaglutide. Two things do come up, though, and they get mixed together constantly — so here is what each one actually is.

    September 7, 2026 · Elena Marsh, Health Writer
  3. A man in a pale blue shirt walks toward the camera on a quiet desert trail

    Semaglutide for Heart Failure Now Has ESC Support

    Europe's 2026 heart-failure guideline now says semaglutide or tirzepatide should be considered for symptomatic patients with obesity and an ejection fraction of at least 45%. The recommendation is about symptoms, walking capacity, and quality of life—not proof that semaglutide prevents death.

    September 7, 2026 · Julian Reyes, Health Writer
  4. A woman in a grey wool cardigan and full-length navy trousers sits in a linen armchair beside a bright window, a plain mug held in both hands

    Tirzepatide Diabetic Retinopathy: Who It's For

    The tirzepatide diabetic retinopathy warning landed on both U.S. labels in August 2026. It asks for eye monitoring in people who already have the condition — not a finding that the medicine harms eyes.

    September 7, 2026 · Priya Raman, Health Writer
  5. A man in a navy long-sleeve jacket and full-length grey trousers walks along a wide gravel path toward the camera, low hills behind him

    Tirzepatide Heart Benefits: Who the Label Covers

    In August 2026 the brand-name version of tirzepatide gained a new use on its label: lowering the risk of heart attack, stroke and cardiac death in adults with type 2 diabetes. Here is what that covers, and what it doesn't.

    September 7, 2026 · Nadia Okonjo, Health Writer
  6. A man in a navy crew-neck jumper and full-length grey trousers sits at a kitchen table peeling an orange

    Tirzepatide vs Ozempic: What You're Comparing

    Ozempic is a brand of semaglutide, approved for type 2 diabetes. Tirzepatide is a different molecule with its own brands — so the comparison most people want is between two drugs, not a drug and a label.

    September 7, 2026 · Julian Reyes, Health Writer
  7. A woman in a blue knit top sits by a bright windowsill holding a plain ceramic mug

    Compounded Tirzepatide Court Ruling Upholds FDA

    The Fifth Circuit left FDA's tirzepatide shortage decision in place. That closes the broad shortage-era compounding route, but it does not erase the narrower rules for an identified patient.

    September 7, 2026 · Priya Raman, Health Writer
  8. A man in a blue shirt arranges oranges in a bright matte-white kitchen

    GLP-1 Patches: Do They Work?

    GLP-1 patches sold online are usually supplement stickers, not semaglutide or tirzepatide. Ordinary patches cannot move these large peptide drugs across intact skin in a predictable dose.

    September 6, 2026 · Julian Reyes, Health Writer
  9. A woman sits at the edge of a raised garden bed holding a small pot of seedlings

    Semaglutide and Aging: The New Study Is in Mice

    A new Nature study found longer life and better physical function in old female mice given semaglutide. It did not test people, so it cannot tell us that semaglutide slows human aging or adds years to human life.

    September 6, 2026 · Elena Marsh, Health Writer
  10. A woman in a sage knit top rests in an armchair with a mug by a window

    Semaglutide L-Carnitine: What the Additive Means

    Some compounders add L-carnitine for its role in fat metabolism. The rationale is real biology, but no human trial shows that mixing it with semaglutide improves weight-loss outcomes.

    September 6, 2026 · Elena Marsh, Health Writer
  11. Two friends sit in armchairs by a window and talk over plain ceramic mugs

    FDA Peptide Warning Letters: What They Mean

    FDA’s five August 24 letters targeted the way online sellers presented injectable peptides for people—not peptide molecules as a class. Here’s what changed, what didn’t, and how a prescription route differs.

    September 6, 2026 · Julian Reyes, Health Writer
  12. A man sits with a mug in an armchair beside a sunlit window in the morning

    Is Semaglutide a GLP-1? What the Class Means

    Yes. Semaglutide is a GLP-1 receptor agonist and an engineered peptide. Those labels describe two different things: the receptor it activates and the structure of the medication.

    September 5, 2026 · Julian Reyes, Health Writer
  13. A woman in a sage shirt and charcoal trousers sits beside a raised garden bed with a small pot of seedlings in her lap

    Semaglutide Pyridoxine: What Vitamin B6 Adds

    Semaglutide/pyridoxine is a compounded combination of semaglutide and vitamin B6. Some compounders add B6 with nausea in mind, but no clinical trial has shown that the combination reduces GLP-1 nausea.

    September 5, 2026 · Priya Raman, Health Writer
  14. A woman in navy knitwear sits by a window holding a plain mug

    Tirzepatide vs Semaglutide Side Effects

    Neither medication has fewer side effects in every setting: dose, treatment population and the individual matter more than a simple ranking.

    September 5, 2026 · Julian Reyes, Health Writer
  15. Two friends in armchairs compare treatment options over plain mugs in a sunlit room

    LillyDirect Tirzepatide vs Compounded Tirzepatide

    LillyDirect supplies branded Zepbound in fixed-strength single-dose vials. Compounded tirzepatide is prepared by a licensed pharmacy for an individual prescription, so it is a different finished product and a different fulfillment route.

    September 4, 2026 · Nadia Okonjo, Health Writer
  16. A woman in a cream jumper and charcoal trousers sits with a mug beside a sunlit window in the morning

    Semaglutide Glycine: Why Some Pharmacies Add It

    Semaglutide with glycine is a compounded combination. Glycine may be described as a formulation aid or wellness additive, but no clinical trial shows that the pairing improves semaglutide outcomes.

    September 4, 2026 · Nadia Okonjo, Health Writer
  17. A woman in a blue shirt and charcoal trousers sits on an entryway bench to lace a sneaker

    Semaglutide Injections: A Practical Guide

    Semaglutide is usually injected once a week, but the device, missed-dose rule, storage window and disposal steps depend on the exact product prescribed.

    September 4, 2026 · Priya Raman, Health Writer
  18. A woman sits on the edge of a raised garden bed holding a pot of seedlings

    Tirzepatide for Weight Loss: What to Know

    Tirzepatide for weight loss is a once-weekly prescription treatment studied alongside diet and physical activity. Here is who SURMOUNT-1 enrolled, what it found, and what long-term care involves.

    September 4, 2026 · Elena Marsh, Health Writer
  19. A woman in a sage jumper and navy trousers sits by a window holding a plain mug

    Does Semaglutide Expire? Pens, Vials, and BUDs

    Yes, semaglutide expires, but the date depends on whether it is an Ozempic pen, a Wegovy single-dose pen, or a compounded vial. The printed expiration date or beyond-use date always wins.

    September 3, 2026 · Julian Reyes, Health Writer
  20. A woman in a cream jumper sits by a window holding a plain ceramic mug

    Is Semaglutide the Same as Ozempic?

    Ozempic is a Novo Nordisk product that contains semaglutide. Compounded semaglutide may name the same base molecule, but it is not Ozempic and the finished products are not interchangeable.

    September 3, 2026 · Julian Reyes, Health Writer

Page 1 of 5 · 88 articles