Muscle & Recovery · Rx only

TB-500, prescribed — not just shipped.

Skip the gray-market guesswork. A licensed clinician reviews your health history, a licensed U.S. pharmacy compounds your prescription, and a care team stays with you after it ships.

$243 / mo$270 as a single month · $648 for a 3-month supply

Start visit

A licensed clinician reviews every request. If TB-500 fits your health history, they write your prescription and your pharmacy takes it from there.

Licensed U.S. providers Licensed U.S. pharmacy All 50 states + D.C.

Requires an online medical evaluation. Prescribed only when a licensed provider determines it's appropriate.

A licensed clinician in a consultation room
TB-500 vial and spec card
TB-500 · Rx only
1

Share your health history

TB-500 has its own online clinical questionnaire — your history, medications, and goals.

2

Your answers get a careful review

A clinician reads your history and takes the time to get it right before anything is prescribed.

3

Your pharmacy ships

Compounded for your prescription and shipped cold-chain, with care-team check-ins after.

The safe way to take TB-500 seriously

TB-500 is easy to find online and hard to trust there. Promise works the way medicine is supposed to work — a clinician decides, a licensed pharmacy fills, and someone stays accountable to you.

A real prescription

Prescribed for you specifically, after a real look at your health history — never pulled off a shelf.

A real pharmacy

Your prescription is compounded for you by a licensed U.S. pharmacy — not a mystery vial from an unregulated website.

Real oversight

Temperature-safe shipping, follow-up check-ins, and a care team that answers — before and after your medication arrives.

Product details
Form
Injectable vial (subcutaneous)
Supply
30-day supply
Pharmacy
Compounded by a licensed U.S. pharmacy
Availability
Ships to all 50 states + D.C.; not all treatments are available in every state

Studied for cell migration

Thymosin beta-4 binds actin, the protein cells use to move. That regulation is the mechanism most of the TB-500 research examines.

A fragment, not the whole protein

TB-500 is built from the active region of a protein present in nearly every human cell, which is why it is studied in tissue-repair models.

Prescribed, never simply supplied

A licensed provider reads your history, decides whether TB-500 fits it, and sets the protocol.

In brief.

TB-500 is a synthetic fragment of thymosin beta-4, a protein your cells already make, and it is studied for one of the least glamorous and most necessary parts of healing: getting repair cells to the place that needs them. Interest in it has grown faster than the clinical evidence, which is why Promise offers it one way only. A licensed provider reviews your health history and prescribes it only when treatment is appropriate for you.

What TB-500 is

Thymosin beta-4 is present in nearly every human cell and is involved in how cells move and how tissue reorganizes itself after damage. TB-500 is a short synthetic peptide based on the active region of that protein — the working end, without the rest of the molecule. It sits in our muscle and recovery category and appears in both of our recovery blends, Wolverine and KLOW.

It is also the peptide most often studied next to BPC-157, and the two get discussed almost interchangeably in places they should not be. They are not the same tool. What they share is that the research on both is largely preclinical, with limited human trial data, so the honest posture is interest rather than certainty.

How it is studied to work

The mechanism research keeps returning to actin. Actin is the structural protein cells use to change shape and crawl, and thymosin beta-4 binds it — regulating the pool of actin a cell can draw on when it needs to move. Studies read TB-500 as acting on that same regulation, which is why cell migration toward a site of injury is the central question in the literature.

Downstream of that, researchers have looked at the formation of new blood vessels and at how tissue organizes itself as it rebuilds, both of which depend on cells arriving where they are needed. Range of motion and post-exertion recovery come up frequently in discussion of the compound. Those are studied questions about a mechanism, not statements about what any individual will experience.

How TB-500 is prescribed

TB-500 has its own intake questionnaire — a different clinical form from every other product we offer, because it is a different clinical decision. You complete it, and a licensed provider reviews your health history, current medications, and what you are trying to address.

They prescribe only when TB-500 is appropriate for you. Not everyone qualifies; requests are declined on medical grounds. If a different approach fits your history better — BPC-157 on its own, a combined protocol, or nothing at all — that is the provider's call to make with you.

What treatment looks like

If you are prescribed, your medication is compounded and dispensed by a licensed U.S. pharmacy, and shipped in discreet, temperature-safe packaging. Your provider sets the protocol from your evaluation; there is no dose to look up, because the right one is a clinical decision about you.

After that, your care team checks in. Adjustments happen with a clinician in the loop, not on your own read of how the week went. TB-500 is designed to sit alongside the fundamentals — sleep, nutrition, and training you can actually recover from — rather than substitute for any of them.

Common questions

What is TB-500?

TB-500 is a synthetic peptide based on the active region of thymosin beta-4, a protein present in nearly every human cell and involved in cell movement and tissue organization. It is studied for cell-migration signaling — specifically its interaction with actin, the structural protein cells use to travel toward damaged tissue — and for the repair processes that depend on it. The published research is largely preclinical, with limited human trial data.

Do I need a prescription for TB-500?

Yes. TB-500 is available through Promise only by prescription. You complete the intake questionnaire for it, a licensed provider reviews your health history, and they prescribe only when treatment is appropriate for you.

Is TB-500 FDA-approved?

No. TB-500 is not FDA-approved. It is a compounded medication, and compounded medications are not reviewed by the FDA for safety, effectiveness, or quality. It is prepared by a licensed U.S. compounding pharmacy against a prescription written for you specifically, after a licensed provider has reviewed your health history.

How does the online visit work?

You start with the intake form for TB-500, which is its own clinical questionnaire — every product has a different one. A licensed provider reviews your answers and prescribes only if TB-500 is appropriate for you. If it is, your medication is compounded and dispensed by a licensed U.S. pharmacy and shipped in temperature-safe packaging, with follow-up check-ins from your care team.

How is TB-500 different from BPC-157?

The two are studied at different points in the repair process. TB-500 is a fragment of thymosin beta-4, and its research centers on actin regulation and cell migration — how repair cells reach the tissue that needs them. BPC-157 is a 15-amino-acid sequence modeled on a protein found in gastric juice, and it is studied for blood-vessel formation signaling and for the gut lining. They are often studied as a pair, which is what our Wolverine protocol combines, and a licensed provider decides which of those options fits your history, if any does.

Related treatments

Other Muscle & Recovery options a provider may consider.

Recovery Wolverine blend vial and spec card

Wolverine

Muscle & Recovery

BPC-157 + TB-500 — the classic two-peptide recovery pairing, prescribed as one blend.

About Wolverine →

$256.50 / moStart visit

Requires an online medical evaluation. Prescribed only when a licensed provider determines it's appropriate.

Recovery KLOW vial and spec card

KLOW

Muscle & Recovery

Four-peptide blend — BPC-157, GHK-Cu, KPV, TB-500 — studied for tissue repair, skin, and recovery support.

About KLOW →

$256.50 / moStart visit

Requires an online medical evaluation. Prescribed only when a licensed provider determines it's appropriate.

Recovery Glow vial and spec card

Glow

Muscle & Recovery

A three-peptide blend of BPC-157, TB-500 and GHK-Cu, pairing the two repair peptides with the copper-binding tripeptide studied around skin and connective tissue.

About Glow →

Coming soonJoin waitlist

Requires an online medical evaluation. Prescribed only when a licensed provider determines it's appropriate.

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