Peptides for anti-aging and longevity
Aging isn't one process — it's cellular housekeeping slowing down on many fronts at once: shorter telomeres, tired mitochondria, slower skin turnover. Peptides for anti-aging (epithalon, GHK-Cu, NAD, and others) each target one of those fronts.
These articles explain the biology in plain terms and are careful about the difference between findings in a lab dish and proven results in people. Everything offered here is prescription-only, reviewed by a licensed provider. None of them stops the clock, and the honest question is always which front matters for you.
18 articles on this topic
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What Is Sermorelin Used For? A Plain Answer
Sermorelin was approved once, for children who were not growing. Adults are prescribed it today for sleep, body composition and recovery — uses that rest on a handful of small studies.
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CJC-1295 Ipamorelin for Women: Evidence and Limits
CJC-1295 with ipamorelin may stimulate the growth-hormone axis, but no clinical trial has tested the combination specifically in women. Perimenopause, estrogen route and the limits of body-composition and sleep evidence all matter to the prescribing decision.
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Semaglutide and Aging: The New Study Is in Mice
A new Nature study found longer life and better physical function in old female mice given semaglutide. It did not test people, so it cannot tell us that semaglutide slows human aging or adds years to human life.
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Tesamorelin for Women: Evidence and Menopause
Tesamorelin for women has limited female-specific evidence: pivotal trials enrolled 84%–86% men, and no trial was designed for menopause-related abdominal change. Hormone therapy, pregnancy, glucose and IGF-1 all change the prescribing conversation.
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Sermorelin for Men: Testosterone, Muscle & Sleep
Sermorelin can stimulate growth-hormone release when the pituitary responds, but it is not testosterone therapy. Small studies in older men found biochemical changes and mixed body-composition or strength results, with no reliable sleep or recovery benefit established.
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Tesamorelin vs CJC-1295: Evidence and Differences
Both peptides signal through the GHRH receptor, but their structures, duration and human evidence differ sharply. The clearest distinction is phase 3 visceral-fat data for tesamorelin versus biomarker studies for CJC-1295.
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SS-31 Benefits: What Human Trials Actually Show
The clearest human evidence for SS-31 is narrow: muscle-strength findings in people with Barth syndrome. Larger trials in other mitochondrial, heart, and eye conditions have produced mixed or negative primary results.
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Is NAD a Peptide? What NAD+ Actually Is
NAD+ is a dinucleotide coenzyme, not a peptide. Its chemistry, cellular jobs, and evidence are different from the peptide therapies it often appears beside.
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Sermorelin for Women: Evidence and Menopause
Sermorelin can raise growth-hormone output in women when the pituitary responds, but female-specific trials are small and mostly use related GHRH compounds. It is not menopause hormone therapy, and the evidence does not show reliable gains in sleep, libido or lean mass for women.
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Epitalon Dosage: How a Prescriber Decides
Published evidence does not establish a standard dose. One small human AEDG study used 0.5 mg daily under the tongue for 20 days; injection-cycle numbers often come from animal work or studies of a different pineal extract.
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Sermorelin Benefits: What the Trials Found
In the best controlled study of GHRH in older adults, nocturnal growth hormone rose, IGF-1 climbed within two weeks, skin thickened — and lean body mass increased in men only. The specificity is the point.
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Ipamorelin Benefits, Side Effects, Legal Status
Developed at Novo Nordisk in the late 1990s, ipamorelin is a five-amino-acid peptide that released growth hormone in animal studies without raising cortisol even at more than 200 times its effective dose.
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Epitalon Benefits, Sorted by Evidence Tier
The most-cited animal experiment gave 54 mice per group monthly doses for life and found mean lifespan unchanged, maximum lifespan up 12.3%, and leukemia down six-fold.
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The Thymulin Peptide Needs Zinc to Work
Thymulin is inert until a zinc ion binds it at a 1:1 molar ratio — and most published results in its literature come from mice, rats, or cell culture.
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SS-31 Peptide: A Patient's Guide to Elamipretide
SS-31 and elamipretide are two names for the same four-amino-acid peptide, and its branded injectable form received accelerated approval from the FDA on September 19, 2025 for a single ultra-rare genetic disease.
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MOTS-c Peptide Benefits: Rodent Depth, Human Hints
MOTS-c is a peptide your mitochondria encode themselves — and it is studied for how cells handle fuel. The rodent evidence runs deep; the human evidence is just beginning.
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GHK-Cu Benefits: The Copper Peptide, Explained
GHK-Cu benefits start from one well-documented fact: blood levels of this three-amino-acid copper peptide fall from roughly 200 ng/mL at age 20 to about 80 ng/mL by age 60.
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A Patient's Guide to NAD+ Injections
NAD+ is a coenzyme found in every living cell, yet most human trial data comes from oral precursors like NR and NMN — including a 2025 meta-analysis in adults with mean ages of 61 to 83 that found no significant muscle benefit.