Topic

Peptides for anti-aging and longevity

Aging isn't one process — it's cellular housekeeping slowing down on many fronts at once: shorter telomeres, tired mitochondria, slower skin turnover. Peptides for anti-aging (epithalon, GHK-Cu, NAD, and others) each target one of those fronts.

These articles explain the biology in plain terms and are careful about the difference between findings in a lab dish and proven results in people. Everything offered here is prescription-only, reviewed by a licensed provider. None of them stops the clock, and the honest question is always which front matters for you.

44 articles on this topic

  1. A man sits on a bench in a utility room with a ball of yarn

    MOTS-c Before and After: What Research Shows

    MOTS-c before and after photos are not clinical evidence. Human research has measured exercise and metabolic markers, but no completed study has published visible results from giving native MOTS-c—the exact peptide, not an altered analogue—to people.

    September 15, 2026 · Nadia Okonjo, Health Writer
  2. A woman sits in an armchair by a bright windowsill holding a plain ceramic mug

    SS-31 Protocol: What the Trials Actually Used

    There is no single SS-31 cycle supported by human research. The useful evidence is narrower: a labeled plan for one rare disease and several trial schedules that cannot be copied into personal dosing advice.

    September 14, 2026 · Priya Raman, Health Writer
  3. A woman seated beside a raised garden bed holds a small pot of seedlings in morning light

    Sermorelin Before and After: A Research Timeline

    The research shows hormone changes within weeks, not a predictable visible transformation. Here is what small adult studies measured at two, six, and 16 weeks.

    September 13, 2026 · Elena Marsh, Health Writer
  4. A man sits cross-legged on a bare exercise mat in an empty room, facing the camera, a single potted plant behind him

    SS-31 and MOTS-c: Can You Take Them Together?

    They are both mitochondrial peptides, and that is about where the similarity stops. No published trial has given people both at once — here is what each one has behind it.

    September 12, 2026 · Nadia Okonjo, Health Writer
  5. A woman in a rust-colored jacket and full-length dark trousers walks toward the camera along a wooded path

    MOTS-c Cycle: Nobody Has Established One

    The word “cycle” came from bodybuilding, not from any MOTS-c research. Every study that has actually given the peptide — the mouse work, and the one human trial now running — dosed it straight through, with no weeks off.

    September 11, 2026 · Priya Raman, Health Writer
  6. A man sits on a wooden bench beneath a window, lacing a running shoe

    MOTS-c Half-Life: What Is Actually Known

    No published study has measured how long the body takes to clear a dose of MOTS-c. Here is what the rodent work, the exercise data and one unpublished Phase 1 trial actually show.

    September 9, 2026 · Priya Raman, Health Writer
  7. A man sits facing the camera on a gym bench, hands resting on his knees, a dumbbell rack out of focus behind him

    What Is Sermorelin Used For? A Plain Answer

    Geref received approvals in 1990 for testing pituitary growth hormone release and in 1997 for children with growth failure from growth hormone deficiency. Adults are prescribed it today for sleep, body composition and recovery — uses that rest on a handful of small studies.

    September 7, 2026 · Nadia Okonjo, Health Writer
  8. A woman in a blue linen shirt and cream trousers holds a seedling pot in a quiet garden

    CJC-1295 Ipamorelin for Women: Evidence and Limits

    CJC-1295 with ipamorelin may stimulate the growth-hormone axis, but no clinical trial has tested the combination specifically in women. Perimenopause, estrogen route and the limits of body-composition and sleep evidence all matter to the prescribing decision.

    September 6, 2026 · Priya Raman, Health Writer
  9. A woman sits at the edge of a raised garden bed holding a small pot of seedlings

    Semaglutide and Aging: The New Study Is in Mice

    A new Nature study found longer life and better physical function in old female mice given semaglutide. It did not test people, so it cannot tell us that semaglutide slows human aging or adds years to human life.

    September 6, 2026 · Elena Marsh, Health Writer
  10. A woman in a rust jacket and charcoal trousers walks toward the camera on a quiet desert trail

    Tesamorelin for Women: Evidence and Menopause

    Tesamorelin for women has limited female-specific evidence: pivotal trials enrolled 84%–86% men, and no trial was designed for menopause-related abdominal change. Hormone therapy, pregnancy, glucose and IGF-1 all change the prescribing conversation.

    September 6, 2026 · Julian Reyes, Health Writer
  11. A seated man in navy athletic wear rests on a bench in a quiet sunlit gym

    Sermorelin for Men: Testosterone, Muscle & Sleep

    Sermorelin can stimulate growth-hormone release when the pituitary responds, but it is not testosterone therapy. Small studies in older men found biochemical changes and mixed body-composition or strength results, with no reliable sleep or recovery benefit established.

    September 5, 2026 · Julian Reyes, Health Writer
  12. A woman in a navy windbreaker and full-length trousers walks toward the camera on a quiet desert trail

    Tesamorelin vs CJC-1295: Evidence and Differences

    Both peptides signal through the GHRH receptor, but their structures, duration and human evidence differ sharply. The clearest distinction is phase 3 visceral-fat data for tesamorelin versus biomarker studies for CJC-1295.

    September 4, 2026 · Priya Raman, Health Writer
  13. A woman walks toward the camera on a quiet desert trail in soft morning light

    SS-31 Benefits: What Human Trials Actually Show

    The clearest human evidence for SS-31 is narrow: muscle-strength findings in people with Barth syndrome. Larger trials in other mitochondrial, heart, and eye conditions have produced mixed or negative primary results.

    September 3, 2026 · Elena Marsh, Health Writer
  14. A woman in a sage shirt sits in an armchair beside a window holding a plain mug

    Is NAD a Peptide? What NAD+ Actually Is

    NAD+ is a dinucleotide coenzyme, not a peptide. Its chemistry, cellular jobs, and evidence are different from the peptide therapies it often appears beside.

    August 30, 2026 · Priya Raman, Health Writer
  15. A woman in a sage knit top and cream trousers holds a ceramic mug beside a window in soft morning light

    Sermorelin for Women: Evidence and Menopause

    Sermorelin can raise growth-hormone output in women when the pituitary responds, but female-specific trials are small and mostly use related GHRH compounds. It is not menopause hormone therapy, and the evidence does not show reliable gains in sleep, libido or lean mass for women.

    August 30, 2026 · Nadia Okonjo, Health Writer
  16. A woman in a cream jumper and charcoal trousers pours tea beside a sunlit kitchen doorway

    Epitalon Dosage: How a Prescriber Decides

    Published evidence does not establish a standard dose. One small human AEDG study used 0.5 mg daily under the tongue for 20 days; injection-cycle numbers often come from animal work or studies of a different pineal extract.

    August 29, 2026 · Nadia Okonjo, Health Writer
  17. A woman in a long-sleeve top and full-length leggings sits mid-stretch on a mat in a bright home studio

    Sermorelin Benefits: What the Trials Found

    In the best controlled study of the modified analogue [Nle27]GHRH(1-29)-NH2 in older adults, nocturnal growth hormone rose, IGF-1 climbed within two weeks, skin thickened — and lean body mass increased in men only. The specificity is the point.

    August 16, 2026 · Nadia Okonjo, Health Writer
  18. A woman in a long-sleeve top doing a seated stretch on a mat in a bright home studio

    Ipamorelin Benefits, Side Effects, Legal Status

    Developed at Novo Nordisk in the late 1990s, ipamorelin is a five-amino-acid peptide that released growth hormone in animal studies without raising cortisol even at more than 200 times its effective dose.

    August 14, 2026 · Nadia Okonjo, Health Writer
  19. A silver-haired woman reading in an armchair by a sunlit window surrounded by houseplants

    Epitalon Benefits, Sorted by Evidence Tier

    The most-cited animal experiment gave 54 mice per group monthly doses for life and found mean lifespan unchanged, maximum lifespan up 12.3%, and leukemia down six-fold.

    August 13, 2026 · Nadia Okonjo, Health Writer
  20. A woman choosing fresh citrus and greens at a sunlit farmers-market stall

    The Thymulin Peptide Needs Zinc to Work

    Thymulin is inert until a zinc ion binds it at a 1:1 molar ratio — and most published results in its literature come from mice, rats, or cell culture.

    August 14, 2026 · Julian Reyes, Health Writer

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