What is epithalon?
Epithalon, also spelled epitalon, is a four-amino-acid peptide (Ala-Glu-Asp-Gly) developed in Russia from research on a pineal-gland extract. It is studied mainly for its effects on telomeres and aging markers. Most of the published work comes from one research group, and much of it is in animals and cells.
These articles cover its history, what the studies measured, side effects, and the claims that go beyond the evidence. Compounded epithalon is not FDA-approved and is prescription-only: a licensed provider reviews every request, and not everyone qualifies.
6 articles on this topic
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Epitalon News Update: October 2026
July brought favorable advisory votes and a new cancer-cell study. Here is what changed for epitalon, what the FDA’s current pages say, and what remains unproven in people.
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Epitalon for Sleep: Better Sleep Isn't Established
Epitalon has been studied for melatonin production, but better sleep hasn't been demonstrated in people. The small human study measured a hormone marker.
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Epitalon Telomeres: What the Studies Actually Show
The claim comes from cells studied outside the body. Those findings haven't established a longer or healthier life for people taking epitalon.
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Is Epitalon FDA Approved? It Is Not
Epitalon is not FDA-approved. Its July 2026 committee recommendation concerned a compounding ingredient list, and FDA has not completed that rulemaking.
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Who Discovered Epitalon? Vladimir Khavinson's Team
Vladimir Khavinson led the team behind epitalon. Its history runs from an animal pineal extract to a four-amino-acid peptide, with conflicting synthesis dates and important limits to the evidence.
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Epitalon Dosage: How a Prescriber Decides
Published evidence does not establish a standard dose. One small human AEDG study used 0.5 mg daily under the tongue for 20 days; injection-cycle numbers often come from animal work or studies of a different pineal extract.