GLP-1 medications
GLP-1 is a hormone your gut releases after you eat — it tells your brain you're full and helps your body manage blood sugar. GLP-1 medications (semaglutide, tirzepatide, and newer molecules) copy that signal, which is why they're so widely studied for weight management and metabolic health.
The articles below explain how these medications work, what the research actually shows, and what side effects and dosing schedules look like in practice. Promise offers compounded GLP-1 medications by prescription only: a licensed provider reviews every request, and not everyone qualifies.
250 articles on this topic
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Does Semaglutide Expire? Pens, Vials, and BUDs
Yes, semaglutide expires, but the date depends on whether it is an Ozempic pen, a Wegovy single-dose pen, or a compounded vial. The printed expiration date or beyond-use date always wins.
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Is Semaglutide the Same as Ozempic?
Ozempic is a Novo Nordisk product that contains semaglutide. Compounded semaglutide may name the same base molecule, but it is not Ozempic and the finished products are not interchangeable.
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Semaglutide for Weight Loss: What It Involves
Semaglutide for weight loss is a prescription treatment used alongside lower-calorie eating and physical activity. Its effects build over months, and individual results depend on continued treatment, tolerability, and clinical fit.
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Tirzepatide Injections: A Practical Guide
Tirzepatide injections deliver prescribed tirzepatide under the skin once weekly. The device may be a prefilled pen, a four-dose KwikPen, or a vial used with a syringe, and each format has its own instructions.
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Does Semaglutide Cause Depression? What We Know
Large trials, cohort studies, and final FDA and European reviews have not found that semaglutide raises depression or suicidality risk. Individual mood changes still deserve prompt attention.
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Foods to Avoid on Tirzepatide: A Practical Guide
There is no universal ban list. Smaller portions and fewer fried, high-fat, fizzy, or alcohol-heavy choices may make nausea, reflux, bloating, and fullness easier to manage.
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How Long Do Peptides Take to Work?
Peptide timelines range from hours on a lab test to months on a scale. The useful answer depends on the molecule, the outcome being measured and the quality of the evidence behind it.
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Peptides With Semaglutide: What the Evidence Says
Evidence gaps depend on the specific peptide combined with semaglutide; cagrilintide–semaglutide has randomized phase 3 trial data, while the combinations discussed here do not. A provider has to judge each compound on its own evidence, risks, and purpose.
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Semaglutide and Pancreatitis: What Studies Show
Randomized trials have not shown more acute pancreatitis with semaglutide than with placebo, but the event is rare and remains a prescribing-label warning. Persistent, severe abdominal pain needs prompt medical attention.
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Semaglutide for Fatty Liver: What Evidence Shows
Semaglutide has strong biopsy-based evidence in adults with MASH and F2–F3 fibrosis. That is narrower than “fatty liver,” and it does not make every semaglutide formulation interchangeable.
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Tirzepatide Pyridoxine: What Vitamin B6 Adds
Tirzepatide/pyridoxine is a compounded combination of tirzepatide and vitamin B6. The B6 is usually included with nausea in mind, but no clinical trial has shown that the combination works better than tirzepatide alone.
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What Are Peptides? A Plain-English Guide
Peptides are short chains of amino acids that the body uses as signals. The same broad family includes natural hormones, established medicines and experimental compounds, so the name alone says little about evidence or safety.
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Semaglutide Before Surgery: Do You Need to Stop?
Most patients can continue semaglutide before an elective procedure, but the plan changes when delayed stomach emptying is more likely. The anesthesia and prescribing teams should make that call together.
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Semaglutide Drug Interactions: What Matters
Most semaglutide interactions are not classic liver-enzyme conflicts. The practical concerns are low blood sugar with insulin or sulfonylureas and altered absorption of oral medicines that need tightly controlled exposure.
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Semaglutide Sulfur Burps: Why They Happen
Sulfur-smelling burps are a real but poorly measured digestive complaint with semaglutide. Trials counted belching, not its smell, and the likely explanation combines slower digestion with hydrogen-sulfide gas.
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Tirzepatide for PCOS: What the Evidence Shows
Early studies connect tirzepatide with weight and metabolic changes in people with PCOS, but the direct evidence is still small. Pregnancy plans and the reason for prescribing matter as much as the diagnosis.
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Tirzepatide Plateau: Why Weight Loss Slows
A tirzepatide plateau is usually the point where a smaller body and stronger biological pressure to maintain weight balance the medication's effects. A brief stall is not the same thing, and a prescriber should review the pattern before changing treatment.
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Is Semaglutide FDA Approved? Not When Compounded
Semaglutide prescribed through Promise is dispensed by a licensed U.S. compounding pharmacy as a compounded medication, which is different from an FDA-approved product: the formulation offered here is not FDA-approved. Ozempic, Rybelsus and Wegovy have approvals for specific uses.
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Semaglutide and Pregnancy: What the Evidence Says
Semaglutide is not recommended for routine weight management during pregnancy. The label calls for a two-month gap before planned conception, while early human exposure data remain limited rather than conclusive.
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Tirzepatide and Birth Control: The 4-Week Rule
Tirzepatide may reduce the absorption of birth control taken by mouth. The current U.S. labels advise non-oral contraception or an added barrier method for four weeks after starting and after every dose increase.
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