Topic

GLP-1 medications

GLP-1 is a hormone your gut releases after you eat — it tells your brain you're full and helps your body manage blood sugar. GLP-1 medications (semaglutide, tirzepatide, and newer molecules) copy that signal, which is why they're so widely studied for weight management and metabolic health.

The articles below explain how these medications work, what the research actually shows, and what side effects and dosing schedules look like in practice. Promise offers compounded GLP-1 medications by prescription only: a licensed provider reviews every request, and not everyone qualifies.

250 articles on this topic

  1. Two friends sit in armchairs with plain mugs during a quiet conversation

    Generic Semaglutide Exists—Just Not in the U.S.

    Canada now has authorized semaglutide generics. The U.S. has only a tentative approval, while compounded semaglutide is another category altogether.

    September 13, 2026 · Julian Reyes, Health Writer
  2. A woman in a cream jumper and charcoal trousers peels an orange at a quiet kitchen counter

    Orforglipron Is Approved: What Foundayo Changes

    Orforglipron is now sold as Foundayo, a once-daily GLP-1 pill for weight management. It removes the fasting rules of oral semaglutide, but it does not replace every reason someone may choose an injection.

    September 13, 2026 · Priya Raman, Health Writer
  3. A woman sits in a linen armchair beside a bright windowsill holding a plain ceramic mug

    Retatrutide Early Access Is Real—and Very Limited

    Retatrutide early access now exists through a narrow, doctor-led program. It is not a public prescription route, a sale, or an approval.

    September 13, 2026 · Nadia Okonjo, Health Writer
  4. A woman in a sage hiking shirt and charcoal trousers sits on a rock beside a quiet desert trail

    Tirzepatide Before and After: An Honest Timeline

    Tirzepatide before and after photos can't tell you what caused a change. The trials give a more useful timeline: early appetite shifts, months of gradual change, and a later plateau that varies widely.

    September 13, 2026 · Priya Raman, Health Writer
  5. A woman sits on a wooden stool at a kitchen counter, peeling an orange over a plain bowl

    Semaglutide and Kidney Disease: The Full Picture

    In the largest trial on the question, serious kidney events were 24% less common on semaglutide than on placebo. The other half of the story is dehydration — and the two keep getting confused.

    September 12, 2026 · Priya Raman, Health Writer
  6. A woman in a rust jacket and full-length trousers walks toward the camera along a wide desert trail, low hills behind her

    Tirzepatide and Blood Pressure: Does It Lower It?

    Yes—blood pressure often falls during tirzepatide treatment, mostly alongside weight loss. That can be welcome, but it also means people taking blood-pressure medicine may need closer review if lightheadedness starts.

    September 12, 2026 · Elena Marsh, Health Writer
  7. A woman sits on the wooden edge of a raised garden bed holding a small pot of seedlings

    Tirzepatide and Gallbladder Risk: Small but Real

    Gallstones turn up in about 1 in 100 people on tirzepatide in the trials — barely above placebo — but inflamed gallbladders are three and a half times as common. Here is why, and the pain pattern that means call someone today.

    September 12, 2026 · Nadia Okonjo, Health Writer
  8. A midlife woman in a blue knit top sits by a bright morning window holding a plain mug

    Tirzepatide and Menopause: What the Evidence Says

    Menopause does not appear to stop tirzepatide from working for weight management. The useful question is whether it fits the whole health picture, including sleep, muscle, bone and any hormone therapy already in use.

    September 12, 2026 · Julian Reyes, Health Writer
  9. A woman in a sage knit top sits by a bright window holding a plain ceramic mug

    Tirzepatide Psoriasis Data Don’t Make It a Treatment

    New 52-week data found better skin and joint outcomes when branded tirzepatide was added to Taltz in adults with psoriatic disease and obesity. That supports treating two linked conditions together—not using tirzepatide alone for psoriasis.

    September 12, 2026 · Elena Marsh, Health Writer
  10. A woman seated at a bright kitchen counter peeling an orange

    Tirzepatide 3 Month Supply: What You Get

    Three months usually means a series of monthly dose packages, not one vial kept open for 90 days. The prescription, storage dates, and billing period each answer a different part of the question.

    September 11, 2026 · Elena Marsh, Health Writer
  11. A woman in a grey wool jumper sits in a linen armchair beside a bright window holding a plain ceramic mug

    What Is Cagrilintide? The Amylin Half of CagriSema

    Cagrilintide is an experimental copy of the appetite hormone amylin, and the other half of Novo Nordisk's CagriSema. It is not approved, it is not sold here, and a US decision is expected before the end of 2026.

    September 11, 2026 · Priya Raman, Health Writer
  12. A woman peels an orange at a quiet kitchen table

    Semaglutide and Tirzepatide Together? Usually No

    Semaglutide and tirzepatide together are not a recommended combination. Both reach the same GLP-1 pathway; a switch should be planned as one treatment replacing the other, with timing and dose set by a prescriber.

    September 10, 2026 · Nadia Okonjo, Health Writer
  13. Two friends seated in armchairs discuss heart health over plain mugs

    GLP-1 Heart Failure Guidelines Changed in 2026

    Europe's 2026 ESC guideline now says semaglutide or tirzepatide should be considered for a narrow group with symptomatic heart failure and obesity. It is an option for a cardiologist to weigh, not a direction to start either drug on your own.

    September 10, 2026 · Nadia Okonjo, Health Writer
  14. A woman sits in a linen armchair beside a bright window, holding a plain ceramic mug in both hands

    How to Choose a Tirzepatide Provider: 7 Checks

    Most of the difference between a careful service and a careless one shows up before a vial ever arrives — in who reads your history, who makes the medicine, and whether anyone answers afterwards.

    September 10, 2026 · Elena Marsh, Health Writer
  15. A woman sits at a kitchen table facing the camera, holding a plain white mug in both hands.

    Mounjaro vs Zepbound: Same Drug, Two Labels

    Both pens hold tirzepatide and run the same dose ladder. What differs is the use printed on the carton — and that is what your insurer reads.

    September 9, 2026 · Priya Raman, Health Writer
  16. A parent peels an orange at a bright kitchen counter

    Semaglutide for Children: What STEP Young Means

    Semaglutide for children ages 6 to 11 has encouraging new trial results, but the news has not changed who can receive Wegovy under its current label. The evidence is promising, early, and best read with a pediatrician.

    September 9, 2026 · Julian Reyes, Health Writer
  17. A woman sits beside a raised garden bed holding a small pot of seedlings

    What Is Semaglutide Used For? A Plain Guide

    Semaglutide has different jobs depending on the brand: blood sugar control, heart or kidney risk reduction, long-term weight management, or certain liver disease. Here is the plain list before a first visit.

    September 9, 2026 · Julian Reyes, Health Writer
  18. A woman in a blue long-sleeve shirt sits on a bench beneath a window, holding a plain ceramic mug in both hands

    Best Tirzepatide Compounding Pharmacy Checklist

    The best choice is a pharmacy you can verify: licensed, tied to a real prescription, clear about sterile preparation, and accountable for the vial after it leaves the building.

    September 8, 2026 · Priya Raman, Health Writer
  19. A woman in a blue knit top peels an orange at a bright kitchen counter

    Tirzepatide Pills Don't Exist. Here's What Does

    There is no oral tirzepatide, either as a brand product or a validated compounded pill. Real GLP-1 tablets contain semaglutide or orforglipron, which are different medicines.

    September 8, 2026 · Nadia Okonjo, Health Writer
  20. A woman sits on the wooden edge of a raised garden bed, a small pot of seedlings held in her lap.

    Zepbound vs Wegovy: Two Drugs, Not Two Brands

    They get compared like two versions of one medicine. They are not — different molecules, different makers, and different lists of what each one is cleared to treat.

    September 8, 2026 · Elena Marsh, Health Writer

Page 8 of 13 · 250 articles