How does selank work?
Selank is a synthetic cousin of tuftsin, an immune-related peptide, developed alongside semax in Russian research. The hypothesis researchers test is calm focus — easing anxious signaling without sedation.
These articles cover how selank is thought to work, what the evidence shows, and how it differs from semax. Standalone Selank is coming soon to Promise; the Semax / Selank blend is offered by prescription after a licensed provider reviews your request. Most of the published research comes from Russian clinical programs, and the articles below are careful about what that does and doesn't tell you.
8 articles on this topic
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Who Discovered Semax? Its Russian Origins
Igor Ashmarin, Nikolai Myasoedov and a Moscow team developed Semax. Its history runs from modified hormone fragments to Russian registration and U.S. review.
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Semax Selank Nasal Spray: What the Route Changes
A Semax Selank nasal spray puts both peptides in one intranasal liquid, but there is no universal recipe. The route, concentration, pump, and prescription all matter—the Russian studies used nasal drops and sprays, while the blend Promise offers by prescription is an injectable vial.
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Selank Dosage: What Human Studies Actually Used
Russian human studies most clearly report 2.7 mg per day intranasally for 14 days, but that fixed study protocol is not a personal dosing guide and does not convert to an injectable Semax/Selank blend.
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Selank for Anxiety: What the Research Shows
Three small Russian trials, 192 patients, and no placebo arm between them. Here is what that evidence supports, what it doesn't, and where US regulators have landed.
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What Is Semax Used For? Evidence and Status
Semax is used in Russia for defined neurological and optic-nerve indications. In the United States, interest centers on focus and memory, but the human evidence for those nootropic uses is small and indirect.
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What Is Selank Used For?
Selank is a Russian-developed heptapeptide studied mostly for anxiety, and its pivotal human trial put 62 patients with generalized anxiety disorder and neurasthenia head to head against the benzodiazepine medazepam.
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The Difference Between Semax and Selank
Both peptides are seven amino acids long and share the same Pro-Gly-Pro tail; what separates them is parentage — Semax comes from a fragment of a pituitary hormone, Selank from a fragment of an antibody.
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Semax Peptide: How It Works in the Brain
How does the Semax peptide work? Most of the mechanism evidence is rodent, the human evidence is intranasal, and the real picture is narrower — and more interesting — than the internet suggests.