What does NAD do?
NAD is a molecule every cell uses to shuttle energy and run repair enzymes — and its levels decline with age, which is why it anchors so much longevity research.
This topic collects our articles on NAD injections and the science around them: what NAD actually does, what supplementation research shows, side effects, and how injectable NAD compares with oral precursors like NMN and NR. Injectable NAD+ is offered by Promise by prescription only, after a provider review. Oral precursors and injections are not interchangeable, and the articles below explain the difference.
14 articles on this topic
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MOTS-c Anti Aging: Human Benefits Remain Unproven
MOTS-c has not been shown to slow aging in people. Mouse findings and human blood measurements answer narrower questions about aging.
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Who Discovered NAD? The History Behind NAD+
Harden and Young found NAD's activity in yeast experiments, with a detailed paper in 1906. The vitamin, Nobel and longevity chapters came later.
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Should I Take NAD+? A Provider's Decision Path
The answer starts with your goal and what is causing the tiredness. Oral supplement findings don't establish what NAD+ injections would do for you.
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NAD+ Myths: 7 Claims Checked Against the Evidence
Some swallowed supplements raise blood NAD+. That doesn't show injections make people younger or that a drip into a vein works better than a shot.
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Should I Take MOTS-c? Start With These Questions
MOTS-c isn't an established treatment for weight loss or tiredness. A provider weighs the thin human evidence, your medicines and sports rules before deciding whether it fits.
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NAD+ News Update: September 2026
Supplements kept raising blood NAD+ this quarter without moving memory, fatigue or sleep scores, and NAD+'s regulatory status stayed where it was. Here is every dated change, June through September.
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NECC Meningitis Outbreak: What Changed After 2012
On September 26, 2012, a Massachusetts compounding pharmacy recalled three lots of steroid injections. The outbreak behind that recall killed 64 people by CDC's count and led Congress to create 503B outsourcing facilities.
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Glutathione Injection Recall: Why People Got Sick
More than 25 people fell ill after IV glutathione, and three Texas pharmacies have recalled vials. FDA traced the problem to one ingredient lot: glutathione powder labeled for supplements, not for a vein.
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NAD IV Death: What the Medical Examiner Found
The NAD IV death of a 27-year-old woman at a Bronx wellness business has been ruled a homicide. The reported cause was air in her IV line: a failure in how the drip was given, rather than a reaction to the drug.
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How Long Do Peptides Take to Work?
Peptide timelines range from hours on a lab test to months on a scale. The useful answer depends on the molecule, the outcome being measured and the quality of the evidence behind it.
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NAD Injection Dosage: What Human Studies Used
There is no validated subcutaneous or intramuscular NAD+ schedule. The best-known IV pharmacokinetic study used 750 mg over six hours, so a prescriber must set route, concentration, amount and frequency together.
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Is NAD a Peptide? What NAD+ Actually Is
NAD+ is a dinucleotide coenzyme, not a peptide. Its chemistry, cellular jobs, and evidence are different from the peptide therapies it often appears beside.
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NAD Injection Side Effects: What Is Reported
Published intravenous data describe transient infusion-associated symptoms in one small retrospective series and no reported adverse events in an earlier slow-infusion pilot; because the studies differed in design and did not randomize infusion rate, they do not establish speed as the cause.
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A Patient's Guide to NAD+ Injections
NAD+ is a coenzyme found in every living cell, yet most human trial data comes from oral precursors like NR and NMN — including a 2025 meta-analysis in adults with mean ages of 61 to 83 that found no significant muscle benefit.