A synthetic small molecule, not a peptide, studied for exercise-like signals in muscle. Evidence comes from cells and mice, including human cells grown in a dish. It is coming soon to Promise.
Coming soon
You are on the list. We will email you when SLU-PP-332 becomes available — and nothing else. Joining is not a medical request, and no prescription has been issued.
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SLU-PP-332 is coming soon to Promise. Add your email and we'll let you know when visits open.
A licensed provider reviews every request; not everyone qualifies.
Every treatment gets its own online clinical questionnaire — your history, medications, and goals.
A real person goes through your history and takes the time to get it right before anything is decided.
If a treatment isn't right for your history, you'll hear that plainly. That review is the whole point.
Made for your prescription by a licensed U.S. pharmacy and shipped in temperature-safe packaging.
Your care team checks in after it arrives. Adjust with your provider, or cancel at any time.
SLU-PP-332 is easy to find online and hard to trust there. Promise works the way medicine is supposed to work — a clinician decides, a licensed pharmacy fills, and someone stays accountable to you.
Prescribed for you specifically, after a real look at your health history — never pulled off a shelf.
Your prescription is compounded for you by a licensed U.S. pharmacy — not a mystery vial from an unregulated website.
Temperature-safe shipping, follow-up check-ins, and a care team that answers — before and after your medication arrives.
Researchers study how this small molecule activates ERRs, proteins that help control how cells use fuel. These are different from estrogen receptors.
The evidence comes from cells and mice, including studies of endurance and fat mass. Research on human cells in a dish does not establish safety in people.
When visits open, a licensed provider will review your history and the early evidence. A request can lead to more questions or a decline.
SLU-PP-332 is a synthetic small molecule, not a peptide. It is studied for how muscle cells use fuel and respond to exercise. The evidence comes from cells and mice, including human cells grown in a dish. We found no human trials of the compound.
SLU-PP-332 is coming soon to Promise — add me to the list. This page explains the research while visits are still closed.
A peptide is a short chain of amino acids, the building blocks of proteins. This compound has a different chemical structure. Researchers designed it to activate estrogen-related receptors, shortened to ERRs. These are proteins that help control which genes, or instructions inside a cell, are active.
Despite their name, ERRs are different from estrogen receptors. They do not bind the body's estrogen. The research here concerns fuel use in muscle, rather than supplying estrogen.
Within energy and focus, this is a question about how cells use energy. The category does not establish that the compound will change how alert or energetic a person feels.
In a 2023 cell and mouse study of ERR activation, a team including Saint Louis University researchers examined muscle gene activity and treadmill endurance. They reported exercise-like patterns of gene activity and longer treadmill running in mice. The endurance response depended on ERR alpha, one member of this protein family.
That is where the phrase exercise mimetic comes from. Mimetic means copying some feature of another process. Here, it refers to signals and measurements that resembled parts of an exercise response under study conditions.
It does not mean the compound reproduces everything that happens during physical activity. The paper did not test whether people could replace movement with a medication. A treadmill result in mice also cannot tell us what a person would feel, or whether using the compound would be safe.
A 2024 mouse study of fat mass and fuel use examined mice with obesity linked to diet or to an inherited change. The authors reported changes in fat mass and the response to insulin, the hormone that helps manage blood sugar. Findings depended on the model: mice eating standard feed showed no change in blood sugar or insulin levels.
That work explains the overlap with metabolic support and fat loss. It does not establish a weight-loss result in people. The studies measured what happened in particular mouse models, under controlled conditions.
A 2025 study using human muscle cells collected tissue from women having hip surgery and added the compound to cells grown in a dish. The women were not given the compound. Human cells can help researchers ask more relevant questions, but they cannot show how a whole person responds.
Our searches of published papers and ClinicalTrials.gov found no human trials of this molecule. Its side effects, interactions with medicines, and safety with longer use in people remain unestablished. Missing human safety data are a gap, not reassurance. The coming-soon label describes availability; it does not change that evidence gap.
MOTS-c is a peptide encoded in mitochondrial DNA. Mitochondria are the parts of cells that turn fuel into usable energy. It is studied as a signal, including through AMPK, a protein involved in how cells use energy.
The compound on this page is a lab-designed small molecule that activates ERRs. Both have drawn interest in exercise-related research, but they are different molecules with different targets. Sharing a research label does not make them interchangeable.
5-Amino-1MQ, also coming soon, is another small molecule rather than a peptide. It is studied for blocking NNMT, an enzyme, or protein that helps run chemical reactions. Its target differs from the ERR proteins studied here. Evidence about one compound cannot be carried over to the other just because both concern metabolism.
When visits open, the first step will be an intake questionnaire written specifically for this compound. It will cover your health history, current medicines and supplements, symptoms, and the reason for your request.
A licensed provider will consider your history alongside the early evidence. They may ask for more information or decline if the compound is not appropriate for you.
If prescribed, a licensed U.S. pharmacy will compound and dispense your medication, with follow-up check-ins from your care team. Your provider sets any protocol; Promise does not publish dosing.
The formulation Promise will offer is not FDA-approved, and no FDA-approved product contains this molecule. Compounded medications are not reviewed by the FDA for safety, effectiveness, or quality. A prescription and clinical follow-up will not turn the existing cell and mouse research into human trial evidence.
It is a synthetic small molecule studied for exercise-like signals in muscle and for how cells use fuel. Researchers examined muscle activity, endurance, and metabolic measures in mice. There is also research on human cells grown in a dish, but we found no trials giving this compound to people.
Yes. When visits open, it will be prescribed by a licensed provider after a review of your health history and compounded for you by a licensed U.S. pharmacy. It will not be a product labeled for laboratory use. The provider will decide whether it is appropriate for you.
A visit will not guarantee a prescription. When visits open, a licensed provider will review your history, current medicines, and reason for the request. They may ask for more information or decline. A place on the waitlist will not bypass that review, and the early evidence will be part of the decision.
No. SLU-PP-332 is not FDA-approved, and no FDA-approved product contains it. The formulation Promise will offer is a compounded medication, which is not reviewed by the FDA for safety, effectiveness, or quality. A prescription will depend on a licensed provider’s review of your health history and whether it is appropriate for you.
Not yet. SLU-PP-332 is coming soon to Promise — add me to the list on this page and we'll email you when visits open. Joining the list is a way to hear about availability. It will not reserve a prescription; a licensed provider will make that decision after reviewing your health history.
It is not a peptide. It is a synthetic small molecule with a different chemical structure from a chain of amino acids, the building blocks of peptides. It activates estrogen-related receptors, or ERRs, which help control how cells use energy. Despite their name, ERRs are different from estrogen receptors.
They are different molecules with different targets. This is a synthetic small molecule that activates ERRs, proteins involved in how cells use fuel. MOTS-c is a peptide encoded in the DNA of mitochondria, the parts of cells that make usable energy. It is studied through signals including AMPK, a protein involved in how cells use energy. Shared interest in exercise-related research does not make them interchangeable.
The difference will be a provider’s review, a prescription, and dispensing by a licensed U.S. pharmacy. Products sold online without a prescription may be labeled for laboratory use and come without those safeguards. When visits open, Promise’s path will include clinical review and follow-up. That oversight will not fill the current gap in human trial evidence.
Other options in Energy & Focus and Metabolic Support & Fat Loss a provider may consider.
Energy & Focus
Nicotinamide adenine dinucleotide, the coenzyme cells use to carry electrons through energy metabolism.
Requires an online medical evaluation. Prescribed only when a licensed provider determines it's appropriate.
Energy & Focus
A 16-amino-acid peptide encoded in mitochondrial DNA, studied for AMPK signaling and metabolic homeostasis. The evidence is mostly preclinical, and every request is reviewed by a provider.
Requires an online medical evaluation. Prescribed only when a licensed provider determines it's appropriate.
Metabolic Support & Fat Loss
Dual-action GLP-1 / GIP for weight management.
Requires an online medical evaluation. Prescribed only when a licensed provider determines it's appropriate.
Metabolic Support & Fat Loss
GLP-1 support for appetite and weight goals.
Requires an online medical evaluation. Prescribed only when a licensed provider determines it's appropriate.
Type a treatment, a goal, or a question.